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Fadi Fakhouri Selected Research

eculizumab

1/2022What is the impact of blood pressure on neurological symptoms and the risk of ESKD in primary and secondary thrombotic microangiopathies based on clinical presentation: a retrospective study.
10/2021Pregnancy-triggered atypical hemolytic uremic syndrome (aHUS): a Global aHUS Registry analysis.
9/2021Eculizumab discontinuation in atypical haemolytic uraemic syndrome: TMA recurrence risk and renal outcomes.
1/2021Eculizumab discontinuation in children and adults with atypical hemolytic-uremic syndrome: a prospective multicenter study.
12/2019Impact of hypertensive emergency and rare complement variants on the presentation and outcome of atypical hemolytic uremic syndrome.
10/2019Outcomes in patients with atypical hemolytic uremic syndrome treated with eculizumab in a long-term observational study.
4/2019Eculizumab prevents thrombotic microangiopathy in patients with atypical haemolytic uraemic syndrome in a long-term observational study.
1/2018Clinical and genetic predictors of atypical hemolytic uremic syndrome phenotype and outcome.
1/2018Patterns of Clinical Response to Eculizumab in Patients With C3 Glomerulopathy.
1/2017Pathogenic Variants in Complement Genes and Risk of Atypical Hemolytic Uremic Syndrome Relapse after Eculizumab Discontinuation.
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Fadi Fakhouri Research Topics

Disease

21Thrombotic Microangiopathies
09/2021 - 06/2005
20Atypical Hemolytic Uremic Syndrome
06/2022 - 12/2008
15Glomerulonephritis
01/2022 - 02/2002
10Hemolytic-Uremic Syndrome
01/2021 - 12/2007
9Chronic Kidney Failure (Chronic Renal Failure)
01/2022 - 08/2003
8Kidney Diseases (Kidney Disease)
06/2022 - 09/2008
7Infections
01/2022 - 07/2005
7Vasculitis (Vasculitides)
01/2022 - 07/2005
7Thrombotic Thrombocytopenic Purpura
11/2020 - 02/2004
6Neoplasms (Cancer)
01/2022 - 07/2005
6Membranoproliferative Glomerulonephritis (Membranoproliferative Glomerulonephritis, Type II)
01/2022 - 09/2008
6Renal Insufficiency (Renal Failure)
09/2021 - 08/2003
6Lipoid Nephrosis (Glomerulonephritis, Minimal Change)
03/2021 - 06/2005
6Nephrotic Syndrome (Syndrome, Nephrotic)
01/2018 - 06/2005
5Inflammation (Inflammations)
01/2022 - 08/2010
5Chronic Renal Insufficiency
01/2021 - 08/2003
5Hemolysis
11/2020 - 12/2008
5Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
03/2020 - 08/2007
5Proteinuria
01/2018 - 08/2003
4Hypertension (High Blood Pressure)
09/2021 - 08/2003
4Membranous Glomerulonephritis (Membranous Nephropathy)
03/2021 - 06/2005
4Pre-Eclampsia (Preeclampsia)
11/2020 - 05/2010
4Thrombosis (Thrombus)
01/2019 - 01/2011
4Fibrosis (Cirrhosis)
01/2018 - 01/2002
3Interstitial Nephritis (Tubulointerstitial Nephritis)
03/2021 - 08/2003
3Malignant Hypertension
01/2021 - 01/2019
3Antiphospholipid Syndrome (Antiphospholipid Antibody Syndrome)
11/2020 - 06/2003
3Eclampsia
11/2020 - 12/2012
3Meningococcal Infections
10/2019 - 01/2016
3Lupus Nephritis
01/2017 - 08/2008
3Necrosis
01/2014 - 09/2008
3Acute Kidney Injury (Acute Renal Failure)
01/2014 - 04/2009
3Fanconi Syndrome (Syndrome, Fanconi)
08/2010 - 09/2005
3Multiple Myeloma
06/2009 - 04/2004
2Hypoxia (Hypoxemia)
03/2022 - 01/2016
2COVID-19
11/2021 - 01/2020
2IGA Glomerulonephritis (IGA Nephropathy)
03/2021 - 05/2009
2Autoimmune Diseases (Autoimmune Disease)
01/2019 - 01/2019
2Pregnancy Complications
05/2010 - 06/2003
2Amyloidosis
09/2008 - 03/2008
2Kidney Cortex Necrosis
07/2005 - 05/2005
1Anemia
03/2022
1Renal Cell Carcinoma (Grawitz Tumor)
01/2022
1Inborn Genetic Diseases (Disease, Hereditary)
01/2022
1Hypocalcemia
01/2022
1Primary Hyperoxaluria (Oxaluria, Primary)
11/2021
1Hyperoxaluria (Oxaluria)
11/2021
1Eosinophilia
04/2021
1IgA Vasculitis (Purpura, Schoenlein Henoch)
03/2021
1Ascites
01/2021

Drug/Important Bio-Agent (IBA)

31Complement System Proteins (Complement)IBA
06/2022 - 03/2007
16eculizumabFDA Link
01/2022 - 12/2012
12Antineutrophil Cytoplasmic Antibodies (ANCA)IBA
01/2022 - 06/2005
8AntibodiesIBA
03/2020 - 09/2005
8Rituximab (Mabthera)FDA Link
01/2019 - 02/2004
6EnzymesIBA
11/2021 - 09/2005
6Biological ProductsIBA
01/2021 - 12/2008
6Immunoglobulin G (IgG)IBA
03/2020 - 02/2002
6SteroidsIBA
01/2018 - 03/2003
6CreatinineIBA
01/2018 - 08/2003
5Complement Inactivating AgentsIBA
06/2022 - 04/2016
5thiamine triphosphorate (TTP)IBA
11/2020 - 08/2005
4Shiga Toxin (Shigella Toxin)IBA
01/2021 - 08/2017
4Complement Factor H (Factor H)IBA
01/2018 - 03/2007
3Immunoglobulins (Immunoglobulin)IBA
01/2022 - 03/2020
3Adrenal Cortex Hormones (Corticosteroids)IBA
01/2020 - 03/2009
3Immunosuppressive Agents (Immunosuppressants)IBA
01/2019 - 11/2009
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2016 - 02/2009
2Transcription Factors (Transcription Factor)IBA
03/2022 - 05/2007
2Complement C3 (C3 Complement)IBA
01/2022 - 01/2019
2AutoantibodiesIBA
01/2022 - 03/2020
2Hemoglobins (Hemoglobin)IBA
01/2021 - 12/2019
2Peroxidase (Myeloperoxidase)IBA
03/2020 - 01/2012
2Membrane Cofactor ProteinIBA
01/2018 - 12/2008
2Anti-Bacterial Agents (Antibiotics)IBA
01/2010 - 07/2009
2AA amyloidosisIBA
05/2009 - 03/2008
2Cyclophosphamide (Cytoxan)FDA LinkGeneric
03/2009 - 02/2004
2Fibrinogen (Factor I)FDA Link
12/2008 - 03/2007
2Immunoglobulin M (IgM)IBA
09/2008 - 03/2008
1IronIBA
03/2022
1factor AIBA
03/2022
1ErythropoietinFDA Link
03/2022
1MagnesiumIBA
01/2022
1MicroRNAs (MicroRNA)IBA
01/2022
1Messenger RNA (mRNA)IBA
01/2022
1claudin 16IBA
01/2022
1OxalatesIBA
11/2021
1Complement C5 (Complement 5)IBA
10/2021
1Antihypertensive Agents (Antihypertensives)IBA
09/2021
1TinIBA
03/2021
1avacopanIBA
02/2021

Therapy/Procedure

15Therapeutics
11/2020 - 08/2003
7Transplantation
01/2022 - 04/2007
5Kidney Transplantation
12/2019 - 11/2011
3Renal Dialysis (Hemodialysis)
04/2021 - 01/2014
3Plasma Exchange
01/2018 - 04/2009
2Aftercare (After-Treatment)
03/2015 - 05/2005
2Stem Cell Transplantation
06/2009 - 05/2007
1Ambulatory Care (Outpatient Care)
09/2021
1Central Venous Catheters
04/2021